Acquired causes of a coagulation disorder, such as neoplasic, infectious and autoimmune Is it all right for me to drink alcoholic beverages at this age? Currently there is no reason to choose a particular type of vaccine. And although yet to be confirmed, it seems the AstraZeneca vaccine, by causing blood clots, may be leading to low platelet levels in an extremely small number of people too. I continue to mask when I have to go to the grocery store, I continue to work entirely remotely , and I minimize my outings and contacts with people whose vaccination status I dont know. COVID-19 Vaccines for People Who Are Moderately or Severely Immunocompromised, Centers for Disease Control and Prevention. The likely mechanism is the other way round, with abnormal clotting leading to low platelet levels. At least 2 months after 3rd dose, Moderna or Pfizer-BioNTech Blood leaves the brain by moving into the venous sinuses (blue) and draining into the jugular vein. Viral vector technology has been used by Janssen for other vaccine development programs. The prevalence of Pulmonary Embolism, in particular was 3.5% in both non-ICU and ICU patients. Both types of vaccines only introduce the gene for a single protein from the virus that causes COVID-19 the spike protein. https://pubmed.ncbi.nlm.nih.gov/32271988/). This pointed the investigators to activity of factor V as well as factor VIII and factor X, two other major clotting factors. All rare bleeding disorder patients (including those with thrombocytopenia and/or platelet function disorders) should be vaccinated. Their findings, based on studies of patients with COVID-19 in Mass General intensive care units (ICUs), point to disturbances in factor V activity as both a potential cause of blood clotting disorders with COVID-19, and to potential methods for identifying at-risk patients with the goal of selecting the proper anticoagulation therapy. The study was internally funded. The comparison between birth control and vaccine blood clots WebA: ACIPs General Best Practice Guidelines state one of the possible disadvantages of combination vaccines includes: adverse events that might occur more frequently after administration of a combination vaccine compared with administration of separate antigens at the same visit, such as fever that occurs with the combination MMRV vaccine and Fact Sheet for Recipients and Caregivers EUA of the Pfizer-BioNTech COVID-19 Vaccine to prevent Coronavirus Disease 2019 in Individuals 16 Years of Age and Older, Fact Sheet for Recipients and Caregivers EUA of the Moderna COVID-19 Vaccine to Prevent Coronavirus Disease 2019 in individuals 18 Years of Age and Older, Janssen COVID-19 Vaccine EUA Fact Sheet for Recipients and Caregivers (fda.gov), COVID-19 Vaccination Considerations for People Who Are Pregnant (CDC), ISTH Interim Guidance for the Diagnosis and Treatment on Vaccine-Induced Immune Thrombotic Thrombocytopenia, Frequently Asked Questions on Vaccine-induced Immune Thrombotic Thrombocytopenia (VITT) (ASH), COVID-19 and Blood Clotting (National Blood Clot Alliance), WFH-EHC April 12, 2021 Statement on COVID-19 Vaccinations, Information for Parents of Children and Adolescents, Information for Health Care and Vaccine Providers, Information for Community Groups and Health Departments. However, if the mRNA vaccine product given for the first two doses is not available or is unknown, either Pfizer-BioNTech or Moderna COVID-19 vaccine (mRNA COVID-19 vaccines) may be administered for the third primary dose. The Pfizer-BioNTech vaccine has been approved by the FDA for the prevention of COVID-19 disease in individuals 16 years of age and older (see question 1 above) but remains available for those individuals 12 through 15 years of age and for the administration of a third dose in certain immunocompromised individuals. If you have a question about this please talk with your hematologist or healthcare professional.