Advertisement. While Activyl is very safe and effective for most pets, I have seen occasional rare reactions in sensitive pets . The impact of the discontinuation of Activyl for cats on the environment will be significant. In warmer climates, fleas are present all year round, while in more temperate climates, fleas are present mainly from late spring through to late fall and even longer . Frontline Plus is an OTC product that uses fipronil and (S)-methoprene to attack fleas and ticks at every life stage. Other adverse reactions reported in decreasing order of frequency are: depression/lethargy, decreased appetite, incoordination, diarrhea, itching, trembling, excessive salivation and seizures. What is the safest and most effective flea and tick treatment for Dogs? Please refer to the information below. An example of data being processed may be a unique identifier stored in a cookie. Just lukewarm water, or water and a mild soap, can help get fleas off your pets fur and skin. Learn More: How to get free cat food battle cats? They are all effective in killing fleas and protecting against flea infestations. 160 Views. The consent submitted will only be used for data processing originating from this website. If activyl is discontinued without a suitable replacement, these consequences . Now that Activyl is being discontinued, pet owners will have to find a new product to protect their cats from fleas and ticks. Bravecto Chew is also effective in killing adult fleas, so it can help reduce the risk of your dog getting flea bite dermatitis. $18.99. Activyl is a topical spot-on treatment for Flea and Intestinal Worm parasites in cats. The parasiticide activyl was discontinued for sale in the U.S. market in August, 2016. Copyright 1995-2023 Merck & Co., Inc., Rahway, NJ, USA and its affiliates. What do you do when frontline doesnt work? The ingredients isopropyl alcohol and indoxacarb are both human-safe, so pets will not be harmed if the product is accidentally ingested. The consent submitted will only be used for data processing originating from this website. [Answer + Alternatives] Petnile, 10.ACTIVYL Flea Treatment for Cats, over 9 lbs, 3 Doses (3-mos. It is also used to prevent flea-allergy dermatitis (an allergy reaction to flea bites). Firstect Plus is the generic equivalent to Frontline Plus for dogs, puppies, cats and kittens 8 weeks and older, Firstect Plus contains Fipronil and (s)-methoprene the active ingredients used in Frontline Plus for cats. The active ingredient in FRONTLINE (fipronil) kills fleas by affecting their nervous system, making them hyperactive before dying. This will likely lead to an increase in the number of flea-borne diseases in cats and humans. The .gov means its official.Federal government websites often end in .gov or .mil. Did Brazil make it to the 2022 World Cup? This post may contain affiliate links. The site is secure. Activyl for cats contains indoxacarb, a flea-killing agent. What is the best flea treatment for large dogs? If your dog or cat experiences any adverse event while using an isoxazoline product, first consult your veterinarian. Zhao X, Ikeda T, Yeh JZ, Narahashi Y. Neurotoxicology 2003;24:8396. Related Read: How often should you change cat litter for two cats? Globalizethis aggregates why was activyl for cats discontinued information to help you offer the best information support options. BIVI made the decision to discontinue activyl after an extenisive review of the product's declining sales and the competitive landscape. However, it's important to remember that the pet industry is a very resilient business. The kill window for flea spray is around 12 hours. A recent study by Merck Animal Health compared the efficacy of two products. Activyl rapidly affects adult fleas following contact or ingestion resulting first in cessation of flea feeding and then causing flea paralysis and death. What is the safest and most effective flea and tick treatment for dogs? This could lead to higher prices for other flea treatments, or a decrease in the quality of products available. Second, the increase in flea infestations will also impact wildlife. However, as an allergy drug, there are numerous complaints about it that can easily make people think they would affect its production. This is because if a dog continually has negative experiences these will make his future . Alternative metabolic pathways (indanone and oxadiazine ring cleavage) in mammals convert indoxacarb mainly to non-toxic metabolites. The manufacturer, Merck, has not stated the reason why they discontinued this innovative and anti-flea pesticide. Is Velvet a good material for a dog collar? For dogs: The most common adverse reaction reported is vomiting. Some of our partners may process your data as a part of their legitimate business interest without asking for consent. Not consenting or withdrawing consent, may adversely affect certain features and functions. Activyl is indicated for the treatment of fleas (Ctenocephalides sp.) Reactivity is rooted in feeling of fear and discomfort. However, like any medicine, there are side effects associated with its use, which may necessitate veterinarian advice. Flea treatment is a big business, and the loss of one of the most popular products will undoubtedly have an impact. Activyl is generally considered to be one of the safest anti-flea and anti-tick treatments ever because several studies showed it was over 98% effective in killing fleas. This could lead to a decrease in sales for the pet industry as a whole. This new product works by being activated by only the flea's enzyme systems into a flea specific mechanism which paralyzes and kills the adult flea. Yes, Activyl for cats and dogs has been discontinued by the manufacturer. Product is available in 5 sizes based on your dog's weight. "When used as directed, ACTIVYL has been shown to kill fleas before they lay eggs for a full month and beyond, 2 which means the product more effectively controlled flea reproduction, and as a. 205 Views. {Alternate Brand Names: ACTIVYL for Dogs or Puppies, ACTIVYL Spot-On for Dogs and Puppies, 2001;132:587-595. Activyl dries quickly after application. You can refer to the answers, The following summaries about unscented goat milk soap will help you make more personal choices about more accurate and faster information. But when it comes to severe infestations and broad-spectrum protection, If you suspect it is not controlling your pets fleas, you may, in certain cases, be able to. I am shocked you treated such a young dog with this kind of product. 4.2 out of 5 Customer Rating. Br J Pharmacol. From Johnathan Hettinger, Midwest Center for Investigative Reporting, March 26: Two pet owners who claim their dogs either died or developed problems after using Seresto flea and tick collars filed a class-action lawsuit this week against Elanco Animal Health, alleging it misrepresented the safety of its product. SENTINEL Flavor Tabs are a monthly oral flea and heartworm prevention medication for dogs and puppies that also protect cats and kittens from fleas. This decrease in sales was likely due to the availability of newer, more effective products on the market. See below for suggested alternatives. You are looking : why was activyl for cats discontinued, The following summaries about what is goat pus will help you make more personal choices about more accurate and faster information. $18.04. Every reactive dog is its own unique case. [Reviews + Alternatives], Vitamin E Oil for Dogs: Dosage for Skin, Warts & Dry Nose, How To Keep Dog From Eating Cat Food: Proven Tips & Tricks, How Much Do Dog Shots Cost at PetSmart: Dog Shot Prices. Activyl is used to prevent fleas from infesting your dog. Finally, some people are concerned about the potential side effects of using activyl on their cats. Activyl Plus for Dogs - 4-11 lbs - Single Photo. This is because the medication kills not only parasites, but also good bacteria that live on the skin and in the gastrointestinal tract. Its a small, liver-flavored chewable tablet available by prescription. I have a 13-week-old puppy, and I used Activyl on him for fleas. For this reason, there was a massive adoption of its use by many pet parents. Free US Shipping! Cats that have been on Activyl for an extended period of time may be at risk for reinfestation if they are no longer treated. [Answer + Alternatives], Vitamin E Oil for Dogs: Dosage for Skin, Warts & Dry Nose. [Find Alternatives]. These are just a few of the many options available for cat owners looking for an alternative to ACTIVYL. Purchasing Bioactivation should be a consideration if this is something you want to consider. Isoxazoline products have been associated with neurologic adverse reactions, including muscle tremors, ataxia, and seizures in some dogs and cats; Although most dogs and cats haven't had. To report suspected adverse drug events for these products and/or obtain a copy of the Safety Data Sheet (SDS) or for technical assistance, contact the appropriate manufacturers at the following phone numbers: Merck Animal Health (Bravecto): 800-224-5318, Elanco Animal Health (Credelio): 888-545-5973, Boehringer Ingelheim (Nexgard): 888-637-4251, Zoetis (Simparica, Revolution Plus): 888-963-8471, If you prefer to report directly to the FDA, or want additional information about adverse drug experience reporting for animal drugs, see, Pet owners and veterinarians who have additional questions can contact. While ACTIVYL was a popular product, there are many other great options available for cat owners looking for a topical solution to protect their feline friend from fleas and ticks. Some are also approved for treatment and control of ear mite infestations and some gastrointestinal parasite infections, and a few are also approved for prevention of heartworm disease. High rate of biological activation in susceptible insects. You can almost see the confusion in his eyes. It takes Activyl 12 hours to kill adult fleas and 8-12 hours to kill newly arriving fleas. Indoxacarb works by bioactivation enzymes inside the flea activate indoxacarb and release its full flea-killing power. All rights reserved. Activyl for . Activyl stops flea feeding, followed by paralysis and death after exposure to product. It is safe and effective when used as directed, but discontinuing use can have consequences for both cats and their owners. Dong K. Insect sodium channels and insecticide resistance. However, as an allergy drug, there are numerous complaints about it that can easily make people think they would affect its production. Various flea and tick insecticides have caused sudden, unprovoked aggression in dogs. All responsible, caring dog and cat owners should adopt these methods, rather than continuing to use insecticides that can cause seizures and death (as with Bravecto) year in and year out on their animals. It treats fleas in all stages (adults, eggs, and larvae), as well as flea allergy dermatitis and lice. Indoxacarb works by bioactivation enzymes inside the flea activate indoxacarb and release its full flea-killing power. Activyl works by targeting the flea's nervous system, leading to paralysis and eventual death. No. ACTIVYL FOR CATS AND KITTENS | Merck Animal Health USA, why was activyl for cats discontinued - mjstudio360.com, Activyl For Cats Discontinued - Claudell Notes - Blogger, why was activyl for dogs discontinued - flyatomicwebmasters.com, Sadly Activyl topical flea product is - Natural Pet Care | Facebook. Cats that are used to receiving regular doses of activyl may experience a sudden change in their energy levels and behavior. It was reported that in some pets, especially cats and dogs, there was persistent salivating caused by the licking of the application site immediately. Activyl was first introduced in 2009, and quickly became one of the most popular flea and tick treatments on the market. Why does my dog still have fleas after frontline? Flea infestations are a major reason why people surrender cats to shelters, and without an effective way to treat them, more cats will be left behind. Can changing cat litter brand make cat sick? Veterinarians recommend Simparica Trio because of its effective protection against ticks and fleas, as well as heartworms, roundworms, and hookwormsall in one convenient monthly chew. What is the number 1 flea treatment for dogs? Activyl contains indoxacarb, which was specifically developed to overcome insect resistance in crop protection. NexGard Soft Chew for Dogs is our top pick because of its effective, fast-acting main ingredient, low-maintenance dosage, and chewable formula. These products have been in use long enough that fleas have adapted and become resistant to them. Wing KD, Sacher M, Kagaya Y, Tsurubuchi Y, Mulderig L, Connair M, Schnee M. Crop Protection. I dont know if its the medicine, but thats the only thing we have changed. What is the safest most effective flea treatment for Dogs? All information published on this website is provided in good faith and for general use only. This will not only be devastating for the cat owners, but also for the cats themselves. Some cats may react mildly to Activyl, but it is safe for use on most cats. The decision to discontinue activyl was likely a difficult one for BIVI. What is the longest lasting flea treatment for Dogs? choices for flea and tick products, as well as heartworm prevention products. It delivers 4 weeks of efficacy against adult fleas on the pet and developing stages of fleas in the pets environment. Is Comfortis for Cats Discontinued? There are several reasons that some cat owners choose not to use activyl for cats. There are safer alternatives to repelling fleas, ticks and other biting insects. [Reviews + Alternatives]. Activyl is labeled to start killing fleas within approximately 8 hours of application. These diseases can affect not only your pet, but everyone in your household. Without a subpoena, voluntary compliance on the part of your Internet Service Provider, or additional records from a third party, information stored or retrieved for this purpose alone cannot usually be used to identify you. It is effective at killing adult and developing stages of fleas and there is no known resistance. These include vomiting, diarrhea, loss of appetite, and increased thirst. document.getElementById( "ak_js_1" ).setAttribute( "value", ( new Date() ).getTime() ); We use technologies like cookies to store and/or access device information. The flea problem is likely to get worse before it gets better, as feral and indoor/outdoor cats that are not treated for fleas will continue to reproduce and spread the pests. This leaves cat owners in a difficult position, as they must decide whether to risk using an ineffective product or to go without flea protection altogether. Is Activyl safe for dogs? Learn More: What to do if my cat has a cold? Some of these products are used monthly, while others are used less often. The discontinuation of Activyl for cats will have a number of impacts on the environment. This could potentially have a serious impact on local ecosystems. The company had to weigh the declining sales of the product against the potential risks associated with its continued sale. Another recently available new topical flea preventative for dogs and cats. His recommendations: Bravecto, NexGard and Simparica. We and our partners use cookies to Store and/or access information on a device. Though they can look the same, they are quite different beasts. This post may contain affiliate links. This meant that fleas were quickly and effectively controlled, preventing them from reproducing and spreading their infestation. Fleas, ticks and sand flies might still be able to transmit any diseases which they may be carrying.. $27.13 Reg Price. Activyl provides selective toxicity through: Indoxacarb produces its potent effects at a unique binding site in voltage-gated sodium ion channels of the nervous system of susceptible insects.4This effect differs strikingly from those reported for other insecticides such as pyrethroids, also known to affect the voltage-dependant sodium channels, but at a different site.1, 2, 4. chevron_right. Kills fleas, & Flea Eggs up to three months and ticks for one month. Until your communication, I was not aware that indoxacarb the highly toxic, hazardous insecticide in Activyl was approved for companion animal use. This results in impaired insect nerve function, feeding cessation, paralysis and death of susceptible insects. by Unfortunately, the manufacturer that produces Activyl flea preventative will no longer be making this product and is being discontinued from their line of flea products. Additionally, flea allergies will become more common as cats are increasingly exposed to the pests. This product has been discontinued by the manufacturer. Acepromazine. It is easy to apply and provides Lapied B, Grolleau F, Sattelle DB. Have you gotten any more reports on this? Activyl Tick Plus combines innovative flea control and proven tick protection to give you and your dog the . This will lead to increased use of other, more harmful products to control fleas, including those that contain toxic chemicals. K9 Advantix II. One possibility is that the company that made activyl for cats decided that it was not profitable enough to continue making the product. The dish soap can help to drown adult fleas. We'll contact your Vet to verify. It remains effective after exposure to sunlight. Why Is My Cat Coughing Fits, Worms & Hairball. Even when treated with a suitable flea control product such a Frontline Plus, Advantage etc it is still possible for your pet to pick up new fleas from the outside environment or other animals. Descriptions: Yes, Activyl for cats and dogs has been discontinued by the manufacturer. No, Cytopoint has not been discontinued and is still on the shelves. You can refer to the answers. Activyl is an innovative flea treatment that is highly effective at killing fleas and preventing infestation. First, without an effective treatment like Activyl, flea infestations in cats will become more common. Activyl is not effective on cats because it only becomes active once in the flea. A. Activyl for Dogs can be administered as early as 8 weeks of age. In this regard, we can conclude that the drug does not have a history of lawsuits.